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IL18 binding protein Rabbit pAb

Cat No.: APA4396
Size:
Product Name: IL18 binding protein Rabbit pAb
Cat No.: APA4396
source: Rabbit
reactivity: Human, Rat
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:2000
IHC: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human IL18 binding protein
calculated molecular weight: 21 kDa
observed molecular weight: 44 kDa
genbank accession number: O95998
gene id (ncbi): 10068
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IL18BPa
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn--s disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]