Cdc6 Rabbit pAb
Cat No.: APA4370
Size：
| Product Name: | Cdc6 Rabbit pAb |
| Cat No.: | APA4370 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:200-1:500 ICC/IF: 1:50-1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Cdc6 |
| calculated molecular weight: | 63 kDa |
| observed molecular weight: | 63 kDa |
| genbank accession number: | Q99741 |
| gene id (ncbi): | 990 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CDC18L; HsCDC6; MGORS5; HsCDC18 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008] |