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Apolipoprotein E Rabbit pAb

Cat No.: APA4359
Size:
Product Name: Apolipoprotein E Rabbit pAb
Cat No.: APA4359
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:50
ICC/IF: 1:50
FC: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Apolipoprotein E
calculated molecular weight: 36 kDa
observed molecular weight: 36 kDa
genbank accession number: P02649
gene id (ncbi): 348
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AD2; LPG; APO-E; ApoE4; LDLCQ5
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]