FDPS Rabbit pAb
Cat No.: APA4351
Size：
| Product Name: | FDPS Rabbit pAb |
| Cat No.: | APA4351 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20-1:100 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human FDPS |
| calculated molecular weight: | 48 kDa |
| observed molecular weight: | 48 kDa |
| genbank accession number: | P14324 |
| gene id (ncbi): | 2224 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | FPS; FPPS; POROK9 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008] |