DKK1 Rabbit pAb
Cat No.: APA4299
Size：
| Product Name: | DKK1 Rabbit pAb |
| Cat No.: | APA4299 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 FC: 1:50 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human DKK1 |
| calculated molecular weight: | 29 kDa |
| observed molecular weight: | 28-40 kDa |
| genbank accession number: | O94907 |
| gene id (ncbi): | 22943 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | SK; DKK-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017] |