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Nucleophosmin Rabbit pAb

Cat No.: APA4277
Size:
Product Name: Nucleophosmin Rabbit pAb
Cat No.: APA4277
source: Rabbit
reactivity: Human
applications: WB,IHC,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:5000
IHC: 1:20-1:100
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Nucleophosmin
calculated molecular weight: 33 kDa
observed molecular weight: 38 kDa
genbank accession number: P06748
gene id (ncbi): 4869
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: B23; NPM
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]