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TCF4 Rabbit pAb

Cat No.: APA4211
Size:
Product Name: TCF4 Rabbit pAb
Cat No.: APA4211
source: Rabbit
reactivity: Human
applications: WB,IHC,FC,ChIP
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:20
FC: 1:20
ChIP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human TCF4
calculated molecular weight: 71 kDa
observed molecular weight: 79 kDa
genbank accession number: P15884
gene id (ncbi): 6925
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: E2-2; ITF2; PTHS; SEF2; FECD3; ITF-2; SEF-2; TCF-4; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; bHLHb19
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box (--E-box--) binding site (--CANNTG--) - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016]