CD276 Rabbit pAb
Cat No.: APA4170
Size：
| Product Name: | CD276 Rabbit pAb |
| Cat No.: | APA4170 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human CD276 |
| calculated molecular weight: | 57 kDa |
| observed molecular weight: | 90-110 kDa |
| genbank accession number: | Q5ZPR3 |
| gene id (ncbi): | 80381 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | B7H3; B7-H3; B7RP-2; 4Ig-B7-H3 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3-- UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |