DRIP130 Rabbit pAb
Cat No.: APA4120
Size:
Product Name: | DRIP130 Rabbit pAb |
Cat No.: | APA4120 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:200 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human DRIP130 |
calculated molecular weight: | 157 kDa |
observed molecular weight: | 130 kDa |
genbank accession number: | Q9ULK4 |
gene id (ncbi): | 9439 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | SUR2; CRSP3; MRT18; SUR-2; ARC130; CRSP130; CRSP133; DRIP130 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012] |