Otx2 Rabbit pAb
Cat No.: APA4090
Size:
Product Name: | Otx2 Rabbit pAb |
Cat No.: | APA4090 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Otx2 |
calculated molecular weight: | 32 kDa |
observed molecular weight: | 32 kDa |
genbank accession number: | P32243 |
gene id (ncbi): | 5015 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CPHD6; MCOPS5 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012] |