Cathepsin K Rabbit pAb
Cat No.: APA4075
Size：
| Product Name: | Cathepsin K Rabbit pAb |
| Cat No.: | APA4075 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Cathepsin K |
| calculated molecular weight: | 37 kDa |
| observed molecular weight: | 37 kDa |
| genbank accession number: | P43235 |
| gene id (ncbi): | 1513 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013] |