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EAAT2 Rabbit pAb

Cat No.: APA4062
Size:
Product Name: EAAT2 Rabbit pAb
Cat No.: APA4062
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human EAAT2
calculated molecular weight: 62 kDa
observed molecular weight: 65 kDa
genbank accession number: P43004
gene id (ncbi): 6506
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HBGT; EAAT2; GLT-1; EIEE41
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]