T-bet/Tbx21 Rabbit pAb
Cat No.: APA4029
Size：
| Product Name: | T-bet/Tbx21 Rabbit pAb |
| Cat No.: | APA4029 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | IHC |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human T-bet/Tbx21 |
| calculated molecular weight: | 58 kDa |
| observed molecular weight: | |
| genbank accession number: | Q9UL17 |
| gene id (ncbi): | 30009 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TBET; T-PET; T-bet; TBLYM |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008] |