ROR gamma Rabbit pAb
Cat No.: APA4024
Size：
| Product Name: | ROR gamma Rabbit pAb |
| Cat No.: | APA4024 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB,IHC,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse ROR gamma |
| calculated molecular weight: | 58 kDa |
| observed molecular weight: | 58 kDa |
| genbank accession number: | P51450 |
| gene id (ncbi): | 19885 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TOR; Thor; Nr1f3; RORgamma |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5---AGGTCA-3-- preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. |