TMS1 Rabbit pAb
Cat No.: APA4023
Size：
| Product Name: | TMS1 Rabbit pAb |
| Cat No.: | APA4023 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human TMS1 |
| calculated molecular weight: | 22 kDa |
| observed molecular weight: | 22 kDa |
| genbank accession number: | Q9ULZ3 |
| gene id (ncbi): | 29108 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ASC; TMS; TMS1; CARD5; TMS-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |