PVRL4 Rabbit pAb
Cat No.: APA4014
Size：
| Product Name: | PVRL4 Rabbit pAb |
| Cat No.: | APA4014 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human PVRL4 |
| calculated molecular weight: | 56 kDa |
| observed molecular weight: | 56 kDa |
| genbank accession number: | Q96NY8 |
| gene id (ncbi): | 81607 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | LNIR; PRR4; EDSS1; PVRL4; nectin-4 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011] |