IL24 Rabbit pAb
Cat No.: APA4008
Size：
| Product Name: | IL24 Rabbit pAb |
| Cat No.: | APA4008 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human IL24 |
| calculated molecular weight: | 24 kDa |
| observed molecular weight: | 24 kDa |
| genbank accession number: | Q13007 |
| gene id (ncbi): | 11009 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | C49A; FISP; MDA7; MOB5; ST16; IL10B |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |