CD137 Rabbit pAb
Cat No.: APA4004
Size:
Product Name: | CD137 Rabbit pAb |
Cat No.: | APA4004 |
source: | Rabbit |
reactivity: | Human |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human CD137 |
calculated molecular weight: | 28 kDa |
observed molecular weight: | 36-40 kDa |
genbank accession number: | Q07011 |
gene id (ncbi): | 3604 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ILA; 4-1BB; CD137; CDw137 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008] |