Fyn Rabbit pAb
Cat No.: APA3962
Size:
Product Name: | Fyn Rabbit pAb |
Cat No.: | APA3962 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:50 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of mouse Fyn |
calculated molecular weight: | 61 kDa |
observed molecular weight: | 61 kDa |
genbank accession number: | P39688 |
gene id (ncbi): | 14360 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | AI448320; AW552119 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. |