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Fyn Rabbit pAb

Cat No.: APA3962
Size:
Product Name: Fyn Rabbit pAb
Cat No.: APA3962
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of mouse Fyn
calculated molecular weight: 61 kDa
observed molecular weight: 61 kDa
genbank accession number: P39688
gene id (ncbi): 14360
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AI448320; AW552119
category: Primary Ab
concentration: 0.5mg/ml
background: Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions.