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Casein Kinase 1 alpha Rabbit pAb

Cat No.: APA3943
Size:
Product Name: Casein Kinase 1 alpha Rabbit pAb
Cat No.: APA3943
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Casein Kinase 1 alpha
calculated molecular weight: 39 kDa
observed molecular weight: 34 kDa
genbank accession number: P48729
gene id (ncbi): 1452
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p
category: Primary Ab
concentration: 0.5mg/ml
background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at --Ser-45--. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).