Nuclear Factor Erythroid Derived 2 Rabbit pAb
Cat No.: APA3853
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| Product Name: | Nuclear Factor Erythroid Derived 2 Rabbit pAb |
| Cat No.: | APA3853 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:50 FC: 1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Nuclear Factor Erythroid Derived 2 |
| calculated molecular weight: | 42 kDa |
| observed molecular weight: | 42 kDa |
| genbank accession number: | Q16621 |
| gene id (ncbi): | 4778 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | p45; NF-E2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. |