TNFRSF18 Rabbit pAb
Cat No.: APA3850
Size：
| Product Name: | TNFRSF18 Rabbit pAb |
| Cat No.: | APA3850 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human TNFRSF18 |
| calculated molecular weight: | 26 kDa |
| observed molecular weight: | 26 kDa |
| genbank accession number: | Q9Y5U5 |
| gene id (ncbi): | 8784 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | AITR; GITR; CD357; GITR-D |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | y |
| This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]: |