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Uroplakin Ia Rabbit pAb

Cat No.: APA3800
Size:
Product Name: Uroplakin Ia Rabbit pAb
Cat No.: APA3800
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Uroplakin Ia
calculated molecular weight: 29 kDa
observed molecular weight: 29 kDa
genbank accession number: O00322
gene id (ncbi): 11045
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: UP1A; UPIA; UPKA; TSPAN21
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
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