NEDD4 Rabbit pAb
Cat No.: APA3799
Size：
| Product Name: | NEDD4 Rabbit pAb |
| Cat No.: | APA3799 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human NEDD4 |
| calculated molecular weight: | 149 kDa |
| observed molecular weight: | 115 kDa |
| genbank accession number: | P46934 |
| gene id (ncbi): | 4734 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | RPF1; NEDD4-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016] |