CD41 Rabbit pAb
Cat No.: APA3659
Size：
| Product Name: | CD41 Rabbit pAb |
| Cat No.: | APA3659 |
| source: | Rabbit |
| reactivity: | Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse CD41 |
| calculated molecular weight: | 113 kDa |
| observed molecular weight: | 113 kDa |
| genbank accession number: | Q9QUM0 |
| gene id (ncbi): | 16399 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CD41; CD41B; GpIIb; AI172977; alphaIIb |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |