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Hsp27 Rabbit pAb

Cat No.: APA3658
Size:
Product Name: Hsp27 Rabbit pAb
Cat No.: APA3658
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:20-1:100
ICC/IF: 1:100
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Hsp27
calculated molecular weight: 23 kDa
observed molecular weight: 27 kDa
genbank accession number: P04792
gene id (ncbi): 3315
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]