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BMP2 Rabbit pAb

Cat No.: APA3657
Size:
Product Name: BMP2 Rabbit pAb
Cat No.: APA3657
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:100
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human BMP2
calculated molecular weight: 45 kDa
observed molecular weight: 30 kDa
genbank accession number: P12643
gene id (ncbi): 650
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BDA2; BMP2A
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]