CCR2 Rabbit pAb
Cat No.: APA3649
Size:
Product Name: | CCR2 Rabbit pAb |
Cat No.: | APA3649 |
source: | Rabbit |
reactivity: | Mouse |
applications: | WB,ICC/IF |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 ICC/IF: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse CCR2 |
calculated molecular weight: | 43 kDa |
observed molecular weight: | 43 kDa |
genbank accession number: | P51683 |
gene id (ncbi): | 12772 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | Ckr2; Ccr2a; Ccr2b; Ckr2a; Ckr2b; mJe-r; Cmkbr2; Cc-ckr-2 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Receptor for the CCL2, CCL7 and CCL12 chemokines (PubMed:8996246). Receptor for the beta-defensin DEFB106A/DEFB106B (By similarity). Transduces a signal by increasing intracellular calcium ion levels (PubMed:8996246). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity). |