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CCR2 Rabbit pAb

Cat No.: APA3649
Size:
Product Name: CCR2 Rabbit pAb
Cat No.: APA3649
source: Rabbit
reactivity: Mouse
applications: WB,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse CCR2
calculated molecular weight: 43 kDa
observed molecular weight: 43 kDa
genbank accession number: P51683
gene id (ncbi): 12772
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: Ckr2; Ccr2a; Ccr2b; Ckr2a; Ckr2b; mJe-r; Cmkbr2; Cc-ckr-2
category: Primary Ab
concentration: 0.5mg/ml
background: Receptor for the CCL2, CCL7 and CCL12 chemokines (PubMed:8996246). Receptor for the beta-defensin DEFB106A/DEFB106B (By similarity). Transduces a signal by increasing intracellular calcium ion levels (PubMed:8996246). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity).