UFD1L Rabbit pAb
Cat No.: APA3639
Size:
Product Name: | UFD1L Rabbit pAb |
Cat No.: | APA3639 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human UFD1L |
calculated molecular weight: | 35 kDa |
observed molecular weight: | 40 kDa |
genbank accession number: | Q92890 |
gene id (ncbi): | 7353 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | UFD1L |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009] |