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UFD1L Rabbit pAb

Cat No.: APA3639
Size:
Product Name: UFD1L Rabbit pAb
Cat No.: APA3639
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
ICC/IF: 1:20
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human UFD1L
calculated molecular weight: 35 kDa
observed molecular weight: 40 kDa
genbank accession number: Q92890
gene id (ncbi): 7353
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: UFD1L
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]