IL33 Rabbit pAb
Cat No.: APA3560
Size：
| Product Name: | IL33 Rabbit pAb |
| Cat No.: | APA3560 |
| source: | Rabbit |
| reactivity: | Mouse, Rat |
| applications: | WB,IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:400 ICC/IF: 1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse IL33 |
| calculated molecular weight: | 30 kDa |
| observed molecular weight: | 30 kDa |
| genbank accession number: | Q8BVZ5 |
| gene id (ncbi): | 77125 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Il-33; Il1f11; NF-HEV; 9230117N10Rik |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury. |