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RUNX3 Rabbit pAb

Cat No.: APA3557
Size:
Product Name: RUNX3 Rabbit pAb
Cat No.: APA3557
source: Rabbit
reactivity: Human
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human RUNX3
calculated molecular weight: 44,46 kDa
observed molecular weight: 44,46 kDa
genbank accession number: Q13761
gene id (ncbi): 864
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AML2; CBFA3; PEBP2aC
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5---PYGPYGGT-3-- found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]