RON Rabbit pAb
Cat No.: APA3556
Size:
Product Name: | RON Rabbit pAb |
Cat No.: | APA3556 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:500 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human RON |
calculated molecular weight: | 152 kDa |
observed molecular weight: | 152 kDa |
genbank accession number: | Q04912 |
gene id (ncbi): | 4486 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | RON; PTK8; CD136; NPCA3; CDw136 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016] |