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Lck Rabbit pAb

Cat No.: APA3553
Size:
Product Name: Lck Rabbit pAb
Cat No.: APA3553
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:200
ICC/IF: 1:20
FC: 1:100
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Lck
calculated molecular weight: 58 kDa
observed molecular weight: 58 kDa
genbank accession number: P06239
gene id (ncbi): 3932
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: LSK; YT16; IMD22; p56lck; pp58lck
category: Primary Ab
concentration: 0.5mg/ml
background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]