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Neurogranin Rabbit pAb

Cat No.: APA3550
Size:
Product Name: Neurogranin Rabbit pAb
Cat No.: APA3550
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:1000
ICC/IF: 1:200
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Neurogranin
calculated molecular weight: 8 kDa
observed molecular weight: 14-16 kDa
genbank accession number: Q92686
gene id (ncbi): 4900
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: RC3; hng
category: Primary Ab
concentration: 0.5mg/ml
background: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]