CD8 alpha Rabbit pAb
Cat No.: APA3549
Size:
Product Name: | CD8 alpha Rabbit pAb |
Cat No.: | APA3549 |
source: | Rabbit |
reactivity: | Mouse |
applications: | WB,IHC,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:500 FC: 1:100 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse CD8 alpha |
calculated molecular weight: | 28 kDa |
observed molecular weight: | 35-42 kDa |
genbank accession number: | P01731 |
gene id (ncbi): | 12525 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | Ly-2; Ly-B; Ly-35; Lyt-2; BB154331 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |