CD8 alpha Rabbit pAb
Cat No.: APA3549
Size：
| Product Name: | CD8 alpha Rabbit pAb |
| Cat No.: | APA3549 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB,IHC,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:500 FC: 1:100 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse CD8 alpha |
| calculated molecular weight: | 28 kDa |
| observed molecular weight: | 35-42 kDa |
| genbank accession number: | P01731 |
| gene id (ncbi): | 12525 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Ly-2; Ly-B; Ly-35; Lyt-2; BB154331 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |