DCTN3 Rabbit pAb
Cat No.: APA3534
Size：
| Product Name: | DCTN3 Rabbit pAb |
| Cat No.: | APA3534 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 IHC: 1:100-1:500 ICC/IF: 1:100-1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human DCTN3 |
| calculated molecular weight: | 21 kDa |
| observed molecular weight: | 21 kDa |
| genbank accession number: | O75935 |
| gene id (ncbi): | 11258 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DCTN22; DCTN-22 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |