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DCTN3 Rabbit pAb

Cat No.: APA3534
Size:
Product Name: DCTN3 Rabbit pAb
Cat No.: APA3534
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:100-1:500
ICC/IF: 1:100-1:500
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human DCTN3
calculated molecular weight: 21 kDa
observed molecular weight: 21 kDa
genbank accession number: O75935
gene id (ncbi): 11258
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DCTN22; DCTN-22
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]