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IDH2 Rabbit pAb

Cat No.: APA3532
Size:
Product Name: IDH2 Rabbit pAb
Cat No.: APA3532
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
FC: 1:20-1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human IDH2
calculated molecular weight: 51 kDa
observed molecular weight: 43 kDa
genbank accession number: P48735
gene id (ncbi): 3418
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IDH; IDP; IDHM; IDPM; ICD-M; D2HGA2; mNADP-IDH
category: Primary Ab
concentration: 0.5mg/ml
background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]