Thrombomodulin Rabbit pAb
Cat No.: APA3531
Size:
Product Name: | Thrombomodulin Rabbit pAb |
Cat No.: | APA3531 |
source: | Rabbit |
reactivity: | Mouse, Rat |
applications: | WB,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse Thrombomodulin |
calculated molecular weight: | 62 kDa |
observed molecular weight: | 95 kDa |
genbank accession number: | P15306 |
gene id (ncbi): | 21824 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | TM; CD141; AI385582 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. |