Renin Rabbit pAb
Cat No.: APA3522
Size：
| Product Name: | Renin Rabbit pAb |
| Cat No.: | APA3522 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | IHC |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Renin |
| calculated molecular weight: | 45 kDa |
| observed molecular weight: | |
| genbank accession number: | P00797 |
| gene id (ncbi): | 5972 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HNFJ2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008] |