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Ryanodine Receptor Rabbit pAb

Cat No.: APA3518
Size:
Product Name: Ryanodine Receptor Rabbit pAb
Cat No.: APA3518
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:500
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Ryanodine Receptor
calculated molecular weight: 565 kDa
observed molecular weight: 565 kDa
genbank accession number: P21817
gene id (ncbi): 6261
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; PPP1R137
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]