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68kDa Neurofilament Rabbit pAb

Cat No.: APA3512
Size:
Product Name: 68kDa Neurofilament Rabbit pAb
Cat No.: APA3512
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:5000
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human 68kDa Neurofilament
calculated molecular weight: 62 kDa
observed molecular weight: 68 kDa
genbank accession number: P07196
gene id (ncbi): 4747
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110
category: Primary Ab
concentration: 0.5mg/ml
background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]