TMEM119 Rabbit pAb
Cat No.: APA3509
Size：
| Product Name: | TMEM119 Rabbit pAb |
| Cat No.: | APA3509 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | IHC |
| clonality: | Polyclonal |
| recommended dilution: | IHC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse TMEM119 |
| calculated molecular weight: | 29 kDa |
| observed molecular weight: | |
| genbank accession number: | Q8R138 |
| gene id (ncbi): | 231633 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | obif; AW208946; BC025600 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Plays an important role in bone formation and normal bone mineralization (PubMed:26207632, PubMed:22416756, PubMed:20025746). Promotes the differentiation of myoblasts into osteoblasts (PubMed:22416756, PubMed:20025746, PubMed:22579779). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed:21239498, PubMed:22579779). Upregulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed:24362451). Essential for normal spermatogenesis and late testicular differentiation (PubMed:26207632). |