BMP4 Rabbit pAb
Cat No.: APA3508
Size:
Product Name: | BMP4 Rabbit pAb |
Cat No.: | APA3508 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000-1:10000 IHC: 1:20 ICC/IF: 1:100 FC: 1:20-1:100 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human BMP4 |
calculated molecular weight: | 47 kDa |
observed molecular weight: | 47 kDa |
genbank accession number: | P12644 |
gene id (ncbi): | 652 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ZYME; BMP2B; OFC11; BMP2B1; MCOPS6 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016] |