TNF alpha Rabbit pAb
Cat No.: APA3506
Size:
Product Name: | TNF alpha Rabbit pAb |
Cat No.: | APA3506 |
source: | Rabbit |
reactivity: | Human, Mouse |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:100 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse TNF alpha |
calculated molecular weight: | 26 kDa |
observed molecular weight: | 17,25,28 kDa |
genbank accession number: | P01375 |
gene id (ncbi): | 7124 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008] |