TIMP1 Rabbit pAb
Cat No.: APA3495
Size：
| Product Name: | TIMP1 Rabbit pAb |
| Cat No.: | APA3495 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse TIMP1 |
| calculated molecular weight: | 23 kDa |
| observed molecular weight: | 26 kDa |
| genbank accession number: | P12032 |
| gene id (ncbi): | 21857 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | EPA; Clgi; Timp; TIMP-1; TPA-S1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. |