ALDH7A1 Rabbit pAb
Cat No.: APA3481
Size：
| Product Name: | ALDH7A1 Rabbit pAb |
| Cat No.: | APA3481 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB,ICC/IF,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human ALDH7A1 |
| calculated molecular weight: | 59 kDa |
| observed molecular weight: | 59 kDa |
| genbank accession number: | P49419 |
| gene id (ncbi): | 501 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | EPD; PDE; ATQ1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011] |