Nodal Rabbit pAb
Cat No.: APA3475
Size：
| Product Name: | Nodal Rabbit pAb |
| Cat No.: | APA3475 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 FC: 1:20-1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Nodal |
| calculated molecular weight: | 40 kDa |
| observed molecular weight: | 40 kDa |
| genbank accession number: | Q96S42 |
| gene id (ncbi): | 4838 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HTX5 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016] |