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Zic2 Rabbit pAb

Cat No.: APA3451
Size:
Product Name: Zic2 Rabbit pAb
Cat No.: APA3451
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IHC: 1:100
ICC/IF: 1:100
FC: 1:200
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Zic2
calculated molecular weight: 55 kDa
observed molecular weight: 55 kDa
genbank accession number: O95409
gene id (ncbi): 7546
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HPE5
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2016]