IL17F Rabbit pAb
Cat No.: APA3418
Size：
| Product Name: | IL17F Rabbit pAb |
| Cat No.: | APA3418 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse IL17F |
| calculated molecular weight: | 18 kDa |
| observed molecular weight: | 18 kDa |
| genbank accession number: | Q7TNI7 |
| gene id (ncbi): | 257630 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | C87042; IL-17F |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (By similarity). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover. Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (By similarity). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation (PubMed:15477493). |