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IL17F Rabbit pAb

Cat No.: APA3418
Size:
Product Name: IL17F Rabbit pAb
Cat No.: APA3418
source: Rabbit
reactivity: Mouse
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse IL17F
calculated molecular weight: 18 kDa
observed molecular weight: 18 kDa
genbank accession number: Q7TNI7
gene id (ncbi): 257630
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: C87042; IL-17F
category: Primary Ab
concentration: 0.5mg/ml
background: Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (By similarity). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover. Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (By similarity). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation (PubMed:15477493).