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Connexin 43/GJA1 Rabbit pAb

Cat No.: APA3383
Size:
Product Name: Connexin 43/GJA1 Rabbit pAb
Cat No.: APA3383
source: Rabbit
reactivity: Human
applications: WB,IHC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:100
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Connexin 43/GJA1
calculated molecular weight: 43 kDa
observed molecular weight: 43 kDa
genbank accession number: P17302
gene id (ncbi): 2697
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HSS; CMDR; CX43; EKVP; GJAL; ODDD; AVSD3; EKVP3; HLHS1; PPKCA
category: Primary Ab
concentration: 0.5mg/ml
background: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]